A Smaller, Deeper, Better Alternative to Traditional Microfracture Procedures

The NanoFx^® (Nanofracture^®) system consists of a reusable hand instrument and a single-use disposable PleuriStik^™ k-wire used to perform a microfracture procedure for the treatment of small, localized articular cartilage defect sites. The 1mm PleuriStik disrupts less surface area than a standard microfracture technique and was purposefully designed to reduce damage to the subchondral plate. It penetrates down to a standardized 9mm depth to reach the targeted marrow cells, three times deeper than comparable microfracture techniques.

When tested against an awl or generic k-wire, NanoFx resulted in thin, fragmented cancellous bone channels without rotational heat generation. It also demonstrated deep cancellous bone perforation with a higher number of open trabecular channels.

The NanoFx handle is available with a 15° angle and as an A-Curve, specifically designed for hard to access ankle lesions.

Key Features & Benefits:

• Disposable, always sharp 1mm PleuriStik with reusable targeting handle is an easy-to-use cell delivery system that disrupts less surface area than a standard microfracture technique, reducing damage to the subchondral plate
• Standardized 9mm perforation depth provides improved access to the targeted marrow cells
• No secondary blood or marrow aspiration step required to access Mysenchymal cells
• No centrifuge or additional equipment necessary to prepare plasma or aspirate
• Compared to traditional microfracture and k-wire stimulation, NanoFx showed superior bone marrow access with multiple trabecular access channels extending 9mm into subchondral bone¹